Lịch sử đối đầu Southampton vs Chelsea |
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| 02.10.2021 | Chelsea | 3-1 | Southampton |  | |
Phong độ của Southampton |
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| 02.04.2022 | Leeds United | 1-1 | Southampton | | ||
| 13.03.2022 | Southampton | 1-2 | Watford | | ||
| 11.03.2022 | Southampton | 1-2 | Newcastle United | | ||
| 05.03.2022 | Aston Villa | 4-0 | Southampton | | ||
| 26.02.2022 | Southampton | 2-0 | Norwich City | | ||
| 19.02.2022 | Southampton | 2-0 | Everton | | ||
| 12.02.2022 | Manchester United | 1-1 | Southampton | | ||
| 10.02.2022 | Tottenham Hotspur | 2-3 | Southampton | | ||
| 23.01.2022 | Southampton | 1-1 | Manchester City | | ||
| 15.01.2022 | Wolves | 3-1 | Southampton | | ||
Phong độ của Chelsea |
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| 02.04.2022 | Chelsea | 1-4 | Brentford | | ||
| 13.03.2022 | Chelsea | 1-0 | Newcastle United | | ||
| 11.03.2022 | Norwich City | 1-3 | Chelsea | | ||
| 05.03.2022 | Burnley | 0-4 | Chelsea | | ||
| 19.02.2022 | Crystal Palace | 0-1 | Chelsea | | ||
| 23.01.2022 | Chelsea | 2-0 | Tottenham Hotspur | | ||
| 19.01.2022 | Brighton Hove Albion | 1-1 | Chelsea | | ||
| 15.01.2022 | Manchester City | 1-0 | Chelsea | | ||
| 02.01.2022 | Chelsea | 2-2 | Liverpool | | ||
| 30.12.2021 | Chelsea | 1-1 | Brighton Hove Albion | | ||