Bắt đầu: 26/10/2024 08:00
Sân: Jorge Abraham Camacho Peregrina
Lịch sử đối đầu Santos Laguna vs Mazatlan FC |
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| 26.02.2024 | Santos Laguna | 1-0 | Mazatlan FC |  | |
| 24.11.2023 | Santos Laguna | 2-1 | Mazatlan FC | | |
| 02.11.2023 | Mazatlan FC | 3-1 | Santos Laguna | | |
Phong độ của Santos Laguna |
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| 23.10.2024 | Santos Laguna | 1-1 | Pachuca | | ||
| 20.10.2024 | Club America | 3-0 | Santos Laguna | | ||
| 07.10.2024 | Santos Laguna | 0-2 | FC Juarez | | ||
| 25.08.2024 | Club Leon | 1-1 | Santos Laguna | | ||
| 19.08.2024 | Club Tijuana | 3-1 | Santos Laguna | | ||
| 10.08.2024 | FC Cincinnati | 1-1 | Santos Laguna | | ||
| 05.08.2024 | Atlanta United | 0-0 | Santos Laguna | | ||
| 01.08.2024 | Santos Laguna | 0-3 | DC United | | ||
| 21.07.2024 | Santos Laguna | 0-3 | Tigres UANL | | ||
| 17.07.2024 | Atlas | 1-0 | Santos Laguna | | ||
Phong độ của Mazatlan FC |
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| 23.10.2024 | Mazatlan FC | 2-0 | Tigres UANL | | ||
| 19.10.2024 | Atlas | 0-0 | Mazatlan FC | | ||
| 05.10.2024 | Mazatlan FC | 2-2 | Queretaro FC | | ||
| 31.08.2024 | Mazatlan FC | 1-1 | Puebla | | ||
| 24.08.2024 | Mazatlan FC | 3-0 | Pachuca | | ||
| 18.08.2024 | Philadelphia Union | 1-1 | Mazatlan FC | | ||
| 14.08.2024 | CDSyC Cruz Azul(N) | 2-2 | Mazatlan FC | | ||
| 10.08.2024 | DC United | 1-2 | Mazatlan FC | | ||
| 01.08.2024 | Nashville | 0-2 | Mazatlan FC | | ||
| 28.07.2024 | New England Revolution | 1-0 | Mazatlan FC | | ||