Lịch sử đối đầu Manchester United vs Southampton |
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| 27.08.2022 | Southampton | 0-1 | Manchester United |  | |
| 12.02.2022 | Manchester United | 1-1 | Southampton | | |
| 22.08.2021 | Southampton | 1-1 | Manchester United | | |
Phong độ của Manchester United |
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| 05.03.2023 | Liverpool | 7-0 | Manchester United | | ||
| 19.02.2023 | Manchester United | 3-0 | Leicester City | | ||
| 12.02.2023 | Leeds United | 0-2 | Manchester United | | ||
| 09.02.2023 | Manchester United | 2-2 | Leeds United | | ||
| 04.02.2023 | Manchester United | 2-1 | Crystal Palace | | ||
| 22.01.2023 | Arsenal | 3-2 | Manchester United | | ||
| 19.01.2023 | Crystal Palace | 1-1 | Manchester United | | ||
| 14.01.2023 | Manchester United | 2-1 | Manchester City | | ||
| 04.01.2023 | Manchester United | 3-0 | AFC Bournemouth | | ||
| 31.12.2022 | Wolves | 0-1 | Manchester United | | ||
Phong độ của Southampton |
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| 05.03.2023 | Southampton | 1-0 | Leicester City | | ||
| 25.02.2023 | Leeds United | 1-0 | Southampton | | ||
| 18.02.2023 | Chelsea | 0-1 | Southampton | | ||
| 11.02.2023 | Southampton | 1-2 | Wolves | | ||
| 04.02.2023 | Brentford | 3-0 | Southampton | | ||
| 21.01.2023 | Southampton | 0-1 | Aston Villa | | ||
| 14.01.2023 | Everton | 1-2 | Southampton | | ||
| 05.01.2023 | Southampton | 0-1 | Nottingham Forest | | ||
| 31.12.2022 | Fulham | 2-1 | Southampton | | ||
| 26.12.2022 | Southampton | 1-3 | Brighton Hove Albion | | ||